Health, Biology, Epidemiology
Identifying and validating network processes of the connectome
The brain project utilises concepts and tools from network science to understand the structural principles of and functional implications for connectomes across species, from the nervous system of the model organism Caenorhabditis elegans, to the mouse, to the human. The brain is inherently multiscale in nature and may be conceptualised as a network at each level; from that of individual neurons and synapses to the integration of macroscopic brain regions. Recent rapid advances in neuroimaging technology and large collaborative efforts are driving an explosion of a wide variety of high quality data, which demand innovative approaches to understand and combine. We aim to tease apart and explain the roles of randomness and order in the complex geometry of and patterns within neural connections, and to develop experimentally testable hypotheses as regards to the fundamental principles behind the observed structure, such as the necessity for the brain to control itself and the body to survive.