The COVID-19 pandemic has underscored the profound influence of social, economic, and demographic disparities on the transmission dynamics of infectious diseases. In this presentation, I will discuss three research papers that delve into the multifaceted impact of various inequalities on the dissemination of SARS-CoV-2. The presented research will cross diverse spatial scales, pandemic phases, and dimensions of inequality, including social inequalities, digital divide, and Global North/South division. The crucial role of data and computational methodologies in gaining insights into how inequality-driven factors have shaped the course of the pandemic will also be discussed. The lessons learnt from similar approaches are a step towards shaping more effective and equitable strategies aimed at mitigating future disease outbreaks.